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Figure Caption
Fig. 3 Mutant axons stall at the roof plate boundary. (A) Time series in an esrom;Kaede embryo shows axons oriented toward the midline and extending and retracting (arrows, see Supplementary Movie 3). After several hours, innervation can be seen developing in the ipsilateral neuropil (arrowhead). (B) Time series of a single mutant growth cone (arrow), maintaining a complex morphology and dynamic behavior for several hours (see Supplementary Movie 4). P: pineal. Scale bar = 20 μm.
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Reprinted from Molecular and cellular neurosciences, 37(2), Hendricks, M., Mathuru, A.S., Wang, H., Silander, O., Kee, M.Z., and Jesuthasan, S., Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation, 271-283, Copyright (2008) with permission from Elsevier. Full text @ Mol. Cell Neurosci.