IMAGE

Fig. 3

ID
ZDB-IMAGE-080211-34
Publication
Lyons et al., 2008 - KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome
All Figures
Figures for Lyons et al., 2008
Image
Figure Caption

Fig. 3 KBP is required for axonal development. Lateral views of PLLn axons in live embryos bearing the Tg(HuC:kaede) transgene at 56 hpf. The images show the segment of the nerve corresponding to about somites 10-16. Axons of the wild type (A) have advanced further posterior than those in the kbpst23 mutant (B). Axonal outgrowth is rescued in kbpst23 mutants injected with full-length wild-type kbp mRNA (C) and the mut2 kbp mRNA (E), but not in kbpst23 mutants injected with the mut1 kbp mRNA (D). Wild-type embryos injected with 2.4 ng of kbp morpholino (F) resemble kbpst23 mutants. In all images, anterior is towards the left and dorsal is towards the top.

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development
Your Input Welcome
We welcome your input and comments. Please use this form to report issues or recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.