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Fig. 5 Angiogenesis is disrupted in scl morphants. Transcripts for fli1 (A, B), hhex (C, D), and efnb2 (E, F) in uninjected and scl morphant embryos. In A, the arrowhead indicates the expression in intersomitic vessels, and in A, C, E–F, the arrow indicates expression in the dorsal aorta. G) Uninjected Tg(lmo2:EGFP) embryos, showing fluorescence in the axial and intersomitic vessels and blood cells. In the presence of increasing amounts scl morpholino (H, I), increased disruption of angiogenesis occurred. All images are lateral views of trunk region, anterior to the left.
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Reprinted from Developmental Biology, 277(2), Dooley, K.A., Davidson, A.J., and Zon, L.I., Zebrafish scl functions independently in hematopoietic and endothelial development, 522-536, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.