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Fig. S4 Forced Notch signaling blocks exocrine differentiation. A–B: expression of ptf1a in control (hsp70:Gal4 neg;UAS:NICD pos or hsp70:Gal4 pos;UAS:NICD neg) and NICD-expressing (hsp70:Gal4 pos;UAS:NICD pos) embryos heat shocked at 24 hpf and analyzed at 32 and 44 hpf. Embryos are in ventral views with anterior to the left. Individual embryos were genotyped by PCR for presence or absence of each transgene.
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Reprinted from Developmental Biology, 301(1), Zecchin, E., Filippi, A., Biemar, F., Tiso, N., Pauls, S., Ellertsdottir, E., Gnugge, L., Bortolussi, M., Driever, W., and Argenton, F., Distinct delta and jagged genes control sequential segregation of pancreatic cell types from precursor pools in zebrafish, 192-204, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.