Fig. 3 β-catenin protein does not localize to the nuclei of hec mutant embryos. Nuclear localization of β-catenin protein was observed in wild-type embryos on the presumptive dorsal side (a, c) but not the presumptive ventral side (b). No nuclear localization was apparent in hec mutant embryos (d–h), β-catenin localization at the membrane can be detected in both wild-type and hec mutant embryos. Animal views of sphere stage embryos (4 hpf). Panels b, c and e–h are higher magnifications of panels a and d, respectively, as indicated by the red boxes in panels a and d. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Reprinted from Developmental Biology, 286(2), Lyman Gingerich, J., Westfall, T.A., Slusarski, D.C., and Pelegri, F., hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequency, 427-439, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.