ZFIN Image: Jin et al., 2007, Fig. 4

Image

Figure Caption

Fig. 4 Mutations affecting vascular tube formation. (A) Epifluorescent micrograph of 36 hpf Tg(flk1:EGFP)^s843 embryo in lateral view (A). White line marks the location of the transverse sections shown in panels B to F. (B–G) Transverse sections of wild-type (B), sih/cmc2 MO injected (C), sol^s828 mutant (D), mts^s233 mutant (E), log^s231 mutant (F), and psn^s634 mutant (G) Tg(flk1:EGFP)^s843 embryos. Lack of circulation does not affect vascular lumen formation (C). Note changes in the number of vascular lumens in sol^s828 and mts^s233 mutant embryos, and in the size and shape of the vascular lumens in log^s231 and psn^s634 mutant embryos.

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Phenotype details

Acknowledgments

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Reprinted from Developmental Biology, 307(1), Jin, S.W., Herzog, W., Santoro, M.M., Mitchell, T.S., Frantsve, J., Jungblut, B., Beis, D., Scott, I.C., D'Amico, L.A., Ober, E.A., Verkade, H., Field, H.A., Chi, N.C., Wehman, A.M., Baier, H., and Stainier, D.Y., A transgene-assisted genetic screen identifies essential regulators of vascular development in vertebrate embryos, 29-42, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.