Gene

pth2ra

ID

ZDB-GENE-991123-10

Name

parathyroid hormone 2 receptor a

Symbol

pth2ra Nomenclature History

Previous Names

pth2r
pthr2 (1)
zPTH2R
zgc:123155 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Exhibits parathyroid hormone receptor activity and peptide receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of membrane. Is expressed in several structures, including blastomere; bone tissue; central nervous system; optic vesicle; and pleuroperitoneal region. Orthologous to human PTH2R (parathyroid hormone 2 receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu1065 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pth2ra Human Ortholog

No data available

Associated With pth2ra Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017983	GPCR, family 2, secretin-like, conserved site
Domain	IPR001879	GPCR, family 2, extracellular hormone receptor domain
Domain	IPR017981	GPCR, family 2-like, 7TM
Family	IPR000832	GPCR, family 2, secretin-like
Family	IPR050332	G-protein coupled receptor 2
Homologous_superfamily	IPR036445	GPCR family 2, extracellular hormone receptor domain superfamily

Domain Details Per Protein

Protein	Length	GPCR, family 2, extracellular hormone receptor domain	GPCR family 2, extracellular hormone receptor domain superfamily	GPCR, family 2-like, 7TM	GPCR, family 2, secretin-like	GPCR, family 2, secretin-like, conserved site	G-protein coupled receptor 2
UniProtKB:A0A8M2BFQ7 InterPro	569
UniProtKB:Q32PR7 InterPro	339
UniProtKB:Q9PWB7 InterPro	575

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ottdart00000002059 (1)	Havana	1,253 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pth2r-201 (1) Ensembl	Ensembl	2,415 nt	Select Tool
mRNA	pth2r-202 (1) Ensembl	Ensembl	1,492 nt	Select Tool
mRNA	pth2ra-203 (1) Ensembl	Ensembl	2,251 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations