Gene
ppm1ab
- ID
- ZDB-GENE-991102-14
- Name
- protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
- Symbol
- ppm1ab Nomenclature History
- Previous Names
-
- pp2ca1
- wu:fd42g12
- zgc:153820
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of canonical Wnt signaling pathway. Predicted to localize to cytosol and nucleus. Orthologous to human PPM1A (protein phosphatase, Mg2+/Mn2+ dependent 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1083 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000222 | PPM-type phosphatase, divalent cation binding |
| Domain | IPR001932 | PPM-type phosphatase-like domain |
| Domain | IPR012911 | Protein serine/threonine phosphatase 2C, C-terminal |
| Family | IPR015655 | Protein phosphatase 2C |
| Homologous_superfamily | IPR036457 | PPM-type phosphatase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | PPM-type phosphatase, divalent cation binding | PPM-type phosphatase-like domain | PPM-type phosphatase-like domain superfamily | Protein phosphatase 2C | Protein serine/threonine phosphatase 2C, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5TZI2
|
372 | |||||
|
UniProtKB:A0A8M2B7B6
|
368 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppm1ab-201
(1)
|
Ensembl | 6,093 nt | ||
| mRNA |
ppm1ab-202
(1)
|
Ensembl | 6,403 nt |
Interactions and Pathways
No data available
Plasmids
No data available