header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-991026-3
Gene Name: tyrosinase
Gene Symbol: tyr
Sequence Ontology ID : SO:0001217

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: oca1, sandy, sdy, tyra (1), zgc:109705

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits catechol oxidase activity. Involved in several processes, including dopamine biosynthetic process from tyrosine; iridophore differentiation; and melanosome organization. Predicted to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ck112a Insertion Exon 1 Premature Stop CRISPR
la019426Tg Transgenic Insertion Unknown Unknown DNA
la027655Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • s901 Unknown Unknown Unknown ENU
    s3555 Point Mutation Unknown Unknown ENU
    te326 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tk20 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm118 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to1 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • to102 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ty79 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tyr_unspecified Unspecified Unknown Unknown
    zf451 Indel Unknown Unknown CRISPR
    Targeting reagents:
    DISEASE ASSOCIATED WITH tyr HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ocular albinism with sensorineural deafness Waardenburg syndrome/albinism, digenic 103470
    oculocutaneous albinism type IA Albinism, oculocutaneous, type IA 203100
    oculocutaneous albinism type IB Albinism, oculocutaneous, type IB 606952
    [Skin/hair/eye pigmentation 3, blue/green eyes] 601800
    [Skin/hair/eye pigmentation 3, light/dark/freckling skin] 601800
    {Melanoma, cutaneous malignant, susceptibility to, 8} 601800
    DISEASE ASSOCIATED WITH tyr VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    oculocutaneous albinism tyrck112a/ck112a standard conditions Park et al., 2016
    color blindness tyrck112a/ck112a standard conditions Park et al., 2016
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process developmental pigmentation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catechol oxidase activity (more)
    GO Terms (all 15)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM tyr No data available
    MARKER RELATIONSHIPS
    tyr Encodes: [EST] aj250302 (1)
    tyr Has Artifact: [cDNA] MGC:109705 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131013 (1)
    Genomic GenBank:CU856545 (1) 111121 bp
    Select Tool
    Polypeptide UniProtKB:F1QDZ4 (1) 535 aa
    Sequence Clusters UniGene:124526 (1)
    Sequence Information (all 34)
    OTHER tyr GENE PAGES
  • Alliance (1)
  • Gene:30207 (1)
  • Ensembl(GRCz11):ENSDARG00000039077 (2)
  • ORTHOLOGY for tyr ( Chr: 15 )
    CITATIONS (120)