Gene

six9

ID

ZDB-GENE-990621-11

Name

SIX homeobox 9

Symbol

six9 Nomenclature History

Previous Names

si:dkey-149j18.3

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure development and negative regulation of transcription, DNA-templated. Predicted to localize to nucleus and transcription factor complex. Orthologous to human SIX2 (SIX homeobox 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu813 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With six9 Human Ortholog

No data available

Associated With six9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR031701	Homeobox protein SIX1, N-terminal SD domain
Homologous_superfamily	IPR009057	Homedomain-like superfamily