Gene

hoxa2b

ID
ZDB-GENE-990415-98
Name
homeobox A2b
Symbol
hoxa2b Nomenclature History
Previous Names
  • hoxa2
  • etID309949.16 (1)
  • Z-75
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; hindbrain neural plate; neural crest; and pharyngeal arch. Orthologous to human HOXA2 (homeobox A2).
Genome Resources
Note
None
Expression
All Expression Data
43 figures from 34 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Microtia with or without hearing impairment (AD) 612290
?Microtia, hearing impairment, and cleft palate (AR) 612290
Associated With hoxa2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001827 Homeobox protein, antennapedia type, conserved site
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR020479 Homeobox domain, metazoa
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox domain, metazoa Homeobox-like domain superfamily Homeobox protein, antennapedia type, conserved site
UniProtKB:O42365 363
UniProtKB:B3DGA4 363
UniProtKB:B3DG99 363
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations