Gene

foxa1

ID
ZDB-GENE-990415-78
Name
forkhead box A1
Symbol
foxa1 Nomenclature History
Previous Names
  • fkd7 (1)
  • forkhead-7
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in axial mesoderm morphogenesis. Predicted to localize to nuclear chromatin. Is expressed in several structures, including central nervous system; chordo neural hinge; digestive system; endoderm; and liver primordium. Orthologous to human FOXA1 (forkhead box A1).
Genome Resources
Note
None
Expression
All Expression Data
61 figures from 52 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Lai et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With foxa1 Human Ortholog
No data available
Associated With foxa1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR013638 Fork-head N-terminal
Domain IPR018533 Forkhead box protein, C-terminal
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Forkhead box protein, C-terminal Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Fork-head N-terminal Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q800Q3 427
UniProtKB:O73783 424
UniProtKB:Q6P0C9 427
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations