Gene

hoxa13a

ID
ZDB-GENE-990415-5
Name
homeobox A13a
Symbol
hoxa13a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in fin development and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; gut; notochord; pectoral fin; and pectoral fin bud. Human ortholog(s) of this gene implicated in Guttmacher syndrome and hand-foot-genital syndrome. Orthologous to human HOXA13 (homeobox A13).
Genome Resources
Note
None
Expression
All Expression Data
15 figures from 7 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa13a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Guttmacher syndrome Alliance ?Guttmacher syndrome 176305
hand-foot-genital syndrome Alliance Hand-foot-uterus syndrome 140000
Associated With hoxa13a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR022067 Homeobox protein Hox1A3 N-terminal
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Homeobox protein Hox1A3 N-terminal
UniProtKB:A3KNK0 310
UniProtKB:Q6W990 310
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations