ZFIN ID: ZDB-GENE-990415-256
Gene Name: nodal-related 1
Gene Symbol: ndr1
Sequence Ontology ID : SO:0000704

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Previous Names: Ndr-1, CHUNP6892, sqt, squint, Znr-2, znr2

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have cytokine activity, transforming growth factor beta receptor binding activity, and type I activin receptor binding activity; involved in several processes, including Spemann  ...
GENE EXPRESSION
All Expression Data: 56 figures from 44 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
cz35 Insertion Unknown Unknown
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi975Tg Transgenic Insertion Exon 2 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la021868Tg Transgenic Insertion Unknown Unknown DNA
    ndr1_unspecified Unspecified Unknown Unknown
    sg7 Insertion Unknown Unknown ZINC_FINGER_NUCLEASE
    sg27 Indel Unknown Unknown TALEN
    sg32 Indel Unknown Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 27 figures from 16 publications
    Observed in:
    DISEASE ASSOCIATED WITH ndr1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    situs inversus Heterotaxy, visceral, 5 270100
    DISEASE ASSOCIATED WITH ndr1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of dorsal identity (more)
    Cellular Component protein-containing complex (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 27)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ndr1-201 (1) 1592
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ndr1
    MARKER RELATIONSHIPS
    ndr1Contained in: [BAC] CH211-220B15 (order this), CH211-263M18 (1) (order this)
    ndr1Contains: [SNP] rs3729101 (1), rs3729102 (1)
    ndr1Encodes: [BAC END] zk5k12.sp6
    [cDNA] MGC:114021 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130966 (1) 1480bp
    Genomic GenBank:AL954771 197721bp
    Select Tool
    Polypeptide UniProtKB:F1QDT8 (1) 392aa
    Sequence Clusters UniGene:20960 (1)
    Sequence Information (all 20)
    OTHER ndr1 GENE PAGES
  • Alliance (1)
  • Gene:799352 (1)
  • VEGA:OTTDARG00000021006 (1)
  • ORTHOLOGY for ndr1 (Chr: 21)
    CITATIONS (210)