Gene
rrm1
- ID
- ZDB-GENE-990415-247
- Name
- ribonucleotide reductase M1 polypeptide
- Symbol
- rrm1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Predicted to be involved in deoxyribonucleotide biosynthetic process. Predicted to localize to ribonucleoside-diphosphate reductase complex. Is expressed in several structures, including immature eye; nervous system; neural tube; presumptive telencephalon; and tail bud. Orthologous to human RRM1 (ribonucleotide reductase catalytic subunit M1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb396 (13 images)
- cb548 (24 images)
- cb838 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 6 | 620647 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000788 | Ribonucleotide reductase large subunit, C-terminal |
| Domain | IPR005144 | ATP-cone domain |
| Domain | IPR013346 | Ribonucleotide reductase, class I, alpha subunit, C-terminal |
| Domain | IPR013509 | Ribonucleotide reductase large subunit, N-terminal |
| Family | IPR039718 | Ribonucleoside-diphosphate reductase large subunit |
| Homologous_superfamily | IPR008926 | Ribonucleotide reductase R1 subunit, N-terminal |
Domain Details Per Protein
| Protein | Length | ATP-cone domain | Ribonucleoside-diphosphate reductase large subunit | Ribonucleotide reductase, class I, alpha subunit, C-terminal | Ribonucleotide reductase large subunit, C-terminal | Ribonucleotide reductase large subunit, N-terminal | Ribonucleotide reductase R1 subunit, N-terminal |
|---|---|---|---|---|---|---|---|
|
UniProtKB:P79732
|
794 | ||||||
|
UniProtKB:F1R2K9
|
794 |
Interactions and Pathways
No data available
Plasmids
No data available