Gene

prph

ID
ZDB-GENE-990415-207
Name
peripherin
Symbol
prph Nomenclature History
Previous Names
  • plasticin
  • zgc:111926
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Involved in tissue regeneration. Predicted to localize to type III intermediate filament. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prph Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis type 1 Alliance {Amyotrophic lateral sclerosis, susceptibility to} 105400
Associated With prph Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR006821 Intermediate filament head, DNA-binding domain
Domain IPR039008 Intermediate filament, rod domain
Family IPR002957 Keratin, type I
Family IPR050405 Intermediate filament structural protein
Domain Details Per Protein
Protein Length Intermediate filament head, DNA-binding domain Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament structural protein Keratin, type I
UniProtKB:Q502Q7 442
UniProtKB:A0A8M6Z374 299
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA prph-201 (1) Ensembl 2745 nt
mRNA prph-202 (1) Havana 2080 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations