Gene
prph
- ID
- ZDB-GENE-990415-207
- Name
- peripherin
- Symbol
- prph Nomenclature History
- Previous Names
-
- plasticin
- zgc:111926
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within tissue regeneration. Predicted to be located in intermediate filament. Predicted to be active in axon; plasma membrane; and type III intermediate filament. Is expressed in nervous system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| amyotrophic lateral sclerosis type 1 | Alliance | {Amyotrophic lateral sclerosis, susceptibility to} | 105400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intermediate filament head, DNA-binding domain | Intermediate filament protein, conserved site | Intermediate filament, rod domain | Intermediate filament structural protein | Keratin, type I |
|---|---|---|---|---|---|---|
|
UniProtKB:Q502Q7
|
442 | |||||
|
UniProtKB:A0A8M6Z374
|
299 |
Interactions and Pathways
No data available
Plasmids
No data available