Gene

pax7a

ID
ZDB-GENE-990415-201
Name
paired box 7a
Symbol
pax7a Nomenclature History
Previous Names
  • pax7 (1)
  • pax7c (1)
  • pax7d (1)
  • pax7e (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in developmental pigmentation; regulation of xanthophore differentiation; and wound healing. Localizes to nucleus. Is expressed in several structures, including central nervous system; muscle; neural crest; neural tube; and post-vent region. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to human PAX7 (paired box 7).
Genome Resources
Note
None
Expression
All Expression Data
54 figures from 34 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 6 from Minchin et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pax7a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
alveolar rhabdomyosarcoma Alliance Rhabdomyosarcoma 2, alveolar 268220
Myopathy, congenital, progressive, with scoliosis 618578
Associated With pax7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR001523 Paired domain
Domain IPR003654 OAR domain
Domain IPR022106 Paired box protein 7, C-terminal
Family IPR043565 PAX family
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily OAR domain Paired box protein 7, C-terminal Paired domain PAX family Winged helix-like DNA-binding domain superfamily
UniProtKB:O57418 507
UniProtKB:A0A2R8RXQ2 274
UniProtKB:O57417 280
UniProtKB:B3DJI1 395
UniProtKB:A0A0R4IM38 487
UniProtKB:O57420 395
UniProtKB:O57419 487
UniProtKB:B3DJR7 275
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations