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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-179
Gene Name: NK2 transcription factor related 7
Gene Symbol: nkx2.7
Sequence Ontology ID : SO:0000704

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Previous Names: nk2.7, nkx2-7, zgc:100762

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in heart development and regulation of cardiac  ...
GENE EXPRESSION
All Expression Data: 9 figures from 7 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
nkx2.7_unrecovered Point Mutation Unknown Unknown ENU
sa7159 Point Mutation Unknown Premature Stop ENU
vu412 Point Mutation Unknown Unknown ENU
vu413 Point Mutation Unknown Frameshift, Premature Stop ENU
Targeting reagents:
DISEASE ASSOCIATED WITH nkx2.7 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
double outlet right ventricle Conotruncal heart malformations 217095
Persistent truncus arteriosus 217095
DISEASE ASSOCIATED WITH nkx2.7 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cardiac muscle cell differentiation (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 14)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA nkx2.7-201 (1) 1176
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM nkx2.7 No data available
MARKER RELATIONSHIPS
nkx2.7Contained in: [BAC] CH211-67O1 (1) (order this)
nkx2.7Encodes: [cDNA] MGC:100762 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131419 (1) 1167bp
Genomic GenBank:BX004845 (1) 165089bp
Select Tool
Polypeptide UniProtKB:Q6AXL1 (1) 269aa
Sequence Clusters UniGene:272 (1)
Sequence Information (all 12)
ORTHOLOGY for nkx2.7 (Chr: 8)
CITATIONS (46)