Gene
nkx2.3
- ID
- ZDB-GENE-990415-178
- Name
- NK2 homeobox 3
- Symbol
- nkx2.3 Nomenclature History
- Previous Names
-
- nk2.3
- nkx2-3
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including cranial ganglion; endoderm; heart; pharyngeal arch; and pharynx. Orthologous to human NKX2-3 (NK2 homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 49 figures from 40 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Yang et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q98871
|
321 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx2.3-201
(1)
|
Ensembl | 1,435 nt | ||
| mRNA |
nkx2.3-202
(1)
|
Ensembl | 814 nt |
Interactions and Pathways
No data available
Plasmids
No data available