Gene
mtnr1bb
- ID
- ZDB-GENE-990415-156
- Name
- melatonin receptor 1Bb
- Symbol
- mtnr1bb Nomenclature History
- Previous Names
-
- mel1br
- mtnr1br
- zMel1b-1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in caudal tuberal nucleus; dorsal caudal thalamic nucleus; periventricular grey zone; periventricular nucleus; and periventricular nucleus of caudal tuberculum. Orthologous to human MTNR1B (melatonin receptor 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| type 2 diabetes mellitus | Alliance | {Diabetes mellitus, type 2, susceptibility to} | 125853 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Melatonin receptor 1A/1B | Melatonin receptor family |
|---|---|---|---|---|---|
|
UniProtKB:P51049
|
347 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mtnr1bb-201
(1)
|
Ensembl | 1,420 nt | ||
| mRNA |
mtnr1bb-202
(1)
|
Ensembl | 1,557 nt |
Interactions and Pathways
No data available
Plasmids
No data available