Gene
mxi1
- ID
- ZDB-GENE-990415-151
- Name
- max interactor 1, dimerization protein
- Symbol
- mxi1 Nomenclature History
- Previous Names
-
- etID309773.22 (1)
- fb16b12
- fb55f03
- wu:fb16b12
- wu:fb55f03
- wu:fd06a08
- wu:fz74f10
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including axial chorda mesoderm; median fin fold; nervous system; neural tube; and periderm. Human ortholog(s) of this gene implicated in neurofibrosarcoma and prostate cancer. Orthologous to human MXI1 (MAX interactor 1, dimerization protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56456 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| prostate cancer | Alliance | Prostate cancer, somatic | 176807 |
| Neurofibrosarcoma, somatic |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|
|
UniProtKB:A3KQG1
|
222 | ||
|
UniProtKB:P50541
|
243 | ||
|
UniProtKB:A3KQG0
|
273 |
Interactions and Pathways
No data available
Plasmids
No data available