Gene

mhc1uba

ID

ZDB-GENE-990415-145

Name

major histocompatibility complex class I UBA

Symbol

mhc1uba Nomenclature History

Previous Names

zgc:91955 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to be involved in immune response. Predicted to localize to external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; asthma (multiple); bone inflammation disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including MR1 (major histocompatibility complex, class I-related).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 6 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91955 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mhc1uba Human Ortholog

No data available

Associated With mhc1uba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site
Domain	IPR001039	MHC class I alpha chain, alpha1 alpha2 domains
Domain	IPR003597	Immunoglobulin C1-set
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR011161	MHC class I-like antigen recognition-like
Family	IPR050208	Antigen-presenting and immune regulatory MHC class I-related
Homologous_superfamily	IPR011162	MHC classes I/II-like antigen recognition protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Homologous_superfamily	IPR037055	MHC class I-like antigen recognition-like superfamily

Domain Details Per Protein

Protein	Length	Antigen-presenting and immune regulatory MHC class I-related	Immunoglobulin C1-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin/major histocompatibility complex, conserved site	MHC classes I/II-like antigen recognition protein	MHC class I alpha chain, alpha1 alpha2 domains	MHC class I-like antigen recognition-like	MHC class I-like antigen recognition-like superfamily
UniProtKB:Q31365 InterPro	348

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mhc1uba-201 (1) Ensembl	Ensembl	1,907 nt	Select Tool
ncRNA	mhc1uba-002 (1) Ensembl	Ensembl	762 nt	Select Tool
ncRNA	mhc1uba-003 (1) Ensembl	Ensembl	881 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations