Gene

psmb8a

ID
ZDB-GENE-990415-141
Name
proteasome 20S subunit beta 8A
Symbol
psmb8a Nomenclature History
Previous Names
  • lmp7
  • psmb8
  • psmb8a (1)
  • beta5ia (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have endopeptidase activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm; nucleus; and proteasome core complex. Human ortholog(s) of this gene implicated in JMP syndrome. Orthologous to human PSMB8 (proteasome 20S subunit beta 8).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmb8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
JMP syndrome Alliance Proteasome-associated autoinflammatory syndrome 1 and digenic forms 256040
Associated With psmb8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016050 Proteasome beta-type subunit, conserved site
Family IPR000243 Peptidase T1A, proteasome beta-subunit
Family IPR001353 Proteasome, subunit alpha/beta
Family IPR023333 Proteasome B-type subunit
Family IPR035705 Proteasome subunit beta type 8
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
Domain Details Per Protein
Protein Length Nucleophile aminohydrolases, N-terminal Peptidase T1A, proteasome beta-subunit Proteasome beta-type subunit, conserved site Proteasome B-type subunit Proteasome, subunit alpha/beta Proteasome subunit beta type 8
UniProtKB:I3ISW4 84
UniProtKB:Q6NZ73 271
UniProtKB:O57330 271
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations