psmb9a

ID

ZDB-GENE-990415-140

Name

proteasome 20S subunit beta 9a

Symbol

psmb9a Nomenclature History

Previous Names

lmp2
psmb9
beta1ia (1)
wu:fa66f04
wu:fj22d05
zgc:91842

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable endopeptidase activity. Acts upstream of or within cellular response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be part of proteasome core complex, beta-subunit complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); lymphoma; and renal cell carcinoma. Orthologous to human PSMB9 (proteasome 20S subunit beta 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91842 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmb9a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Proteasome-associated autoinflammatory syndrome 6	620796

Associated With psmb9a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR016050	Proteasome beta-type subunit, conserved site
Family	IPR000243	Peptidase T1A, proteasome beta-subunit
Family	IPR001353	Proteasome, subunit alpha/beta
Family	IPR023333	Proteasome B-type subunit
Homologous_superfamily	IPR029055	Nucleophile aminohydrolases, N-terminal