Gene

hoxd3a

ID

ZDB-GENE-990415-120

Name

homeobox D3a

Symbol

hoxd3a Nomenclature History

Previous Names

hoxd3
im:7144208 (1)
Z-56

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; embryonic skeletal system morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; neural tube; pectoral fin bud; and spinal cord. Orthologous to human HOXD3 (homeobox D3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7144208 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxd3a Human Ortholog

No data available

Associated With hoxd3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001827	Homeobox protein, antennapedia type, conserved site
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Domain	IPR020479	Homeodomain, metazoa
Domain	IPR025281	Domain of unknown function DUF4074
Homologous_superfamily	IPR009057	Homedomain-like superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Domain of unknown function DUF4074	Homedomain-like superfamily	Homeobox, conserved site	Homeobox protein, antennapedia type, conserved site	Homeodomain	Homeodomain, metazoa
UniProtKB:O42370	InterPro	396
UniProtKB:A0A8M9PRW4	InterPro	396

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	hoxd3a-201 (1) Ensembl	Ensembl	2,567 nt	Select Tool ZFIN BLAST
mRNA	hoxd3a-203 (1) Ensembl	Ensembl	1,970 nt	Select Tool ZFIN BLAST
mRNA	hoxd3a-204 (1) Ensembl	Ensembl	1,919 nt	Select Tool ZFIN BLAST
ncRNA	hoxd3a-002 (1) Ensembl	Ensembl	480 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:pBS ZfHoxd3a

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations