ZFIN ID: ZDB-GENE-990415-116
Gene Name: homeobox D10a
Gene Symbol: hoxd10a    Nomenclature History

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Previous Names: hoxd-10, hoxd10, z-82

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Is expressed in mesenchyme; mesenchyme pectoral fin; pectoral fin bud; and pectoral fin field. Orthologous to human HOXD10 (homeobox D10).
Genome Resources: Alliance (1),  Gene:30404 (1),  Ensembl(GRCz11):ENSDARG00000057859 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13761 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21418 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hoxd10a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hoxd10a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital vertical talus Alliance Charcot-Marie-Tooth disease, foot deformity of 192950
    Vertical talus, congenital 192950
    DISEASE ASSOCIATED WITH hoxd10a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process multicellular organism development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001356 Homeobox domain
    Homologous_superfamily IPR009057 Homeobox-like domain superfamily
    Conserved_site IPR017970 Homeobox, conserved site
    Domain IPR020479 Homeobox domain, metazoa
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxd10a-201 (1)    Ensembl 1650
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxd10a No data available
    MARKER RELATIONSHIPS
    hoxd10a Contained in: [BAC] RP71-78H1 (1)
    hoxd10a Encodes: [cDNA] MGC:86636 (1), MGC:174768 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131166 (1) 1032 bp
    Genomic GenBank:BX322661 (1) 146527 bp
    Select Tool
    Polypeptide UniProtKB:Q90469 (1) 332 aa
    Sequence Information (all 29)
    ORTHOLOGY for hoxd10a ( Chr: 9 )
    CITATIONS (43)