ZFIN ID: ZDB-GENE-990415-108
Gene Name: homeobox B8a
Gene Symbol: hoxb8a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: gp-8, hoxb8, fj67g02, wu:fj67g02 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in cell population proliferation and posterior lateral line neuromast primordium migration. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neural tube; pancreatic system; paraxial mesoderm; and pronephros. Orthologous to human HOXB8 (homeobox B8).
Genome Resources: Alliance (1),  Gene:30343 (1),  Ensembl(GRCz11):ENSDARG00000056027 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14443 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hoxb8a N/A 2
    MO2-hoxb8a N/A 1
    DISEASE ASSOCIATED WITH hoxb8a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hoxb8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell population proliferation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxb8a-201 (1)    Ensembl 1817
    ottdart00000001809 (1) 1752
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene:Hox B8a
    CONSTRUCTS WITH SEQUENCES FROM hoxb8a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(5xUAS:hoxb8a-MYC,cryaa:RFP) cryaaUAS hoxb8aRFP Danio rerio 1 4
    Tg(5xUAS:hoxb8a-VP16,cryaa:RFP) cryaaUAS hoxb8aRFP Danio rerio 1 3
    Tg(5xUAS:hoxb8aDR-HA,cryaa:RFP) cryaaUAS hoxb8aRFP Danio rerio 1 3
    MARKER RELATIONSHIPS
    hoxb8a Contained in: [BAC] CH211-72A16 (1)
    [PAC] BUSM1-254O17 (1)
    hoxb8a Encodes: [EST] fj67g02
    [cDNA] MGC:64159 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131120 (1) 1821 nt
    Genomic GenBank:BX927395 (1) 152987 nt
    Select Tool
    Polypeptide UniProtKB:Q8AWZ0 (1) 245 aa
    Sequence Information (all 18)
    ORTHOLOGY for hoxb8a ( Chr: 3 )
    CITATIONS (50)