Gene

ube2kb

ID

ZDB-GENE-980605-9

Name

ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)

Symbol

ube2kb Nomenclature History

Previous Names

ube2k
hip2 (1)
zgc:103472

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have ubiquitin conjugating enzyme activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Predicted to localize to nucleus. Is expressed in lens. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6892623 (2 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ube2kb Human Ortholog

No data available

Associated With ube2kb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR023313	Ubiquitin-conjugating enzyme, active site
Domain	IPR000608	Ubiquitin-conjugating enzyme E2
Domain	IPR015940	Ubiquitin-associated domain
Domain	IPR042599	Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain
Family	IPR050113	Ubiquitin-conjugating enzyme
Homologous_superfamily	IPR009060	UBA-like superfamily
Homologous_superfamily	IPR016135	Ubiquitin-conjugating enzyme/RWD-like