foxd5

ID

ZDB-GENE-980605-4

Name

forkhead box D5

Symbol

foxd5 Nomenclature History

Previous Names

fkd8 (1)
forkhead-8
zgc:114027

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within somite rostral/caudal axis specification. Predicted to be located in nucleus. Is expressed in several structures, including margin; midbrain neural plate; paraxial mesoderm; presumptive paraxial mesoderm; and shield. Orthologous to human FOXD4 (forkhead box D4); FOXD4L4 (forkhead box D4 like 4); and FOXD4L5 (forkhead box D4 like 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Lee et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxd5 Human Ortholog

No data available

Associated With foxd5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018122	Fork head domain conserved site1
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Family	IPR050211	Forkhead box domain-containing protein
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily