ZFIN is now using GRCz12tu for Genomic Data
Gene
pou6f1
- ID
- ZDB-GENE-980526-530
- Name
- POU class 6 homeobox 1
- Symbol
- pou6f1 Nomenclature History
- Previous Names
-
- pou[c]
- pouc (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within atrioventricular canal morphogenesis. Predicted to be located in nucleus. Is expressed in atrioventricular canal; atrium; cardiac ventricle; central nervous system; and telencephalon. Orthologous to human POU6F1 (POU class 6 homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Bhakta et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-specific domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z4C6 | InterPro | 574 | ||||||
| UniProtKB:P31367 | InterPro | 610 | ||||||
| UniProtKB:A0A2R8QIA3 | InterPro | 595 | ||||||
| UniProtKB:A0AB32TA53 | InterPro | 609 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou6f1-201
(1)
|
Ensembl | 4,090 nt | ||
| mRNA |
pou6f1-202
(1)
|
Ensembl | 525 nt | ||
| mRNA |
pou6f1-203
(1)
|
Ensembl | 1,871 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers