ZFIN is now using GRCz12tu for Genomic Data
Gene
pou6f1
- ID
- ZDB-GENE-980526-530
- Name
- POU class 6 homeobox 1
- Symbol
- pou6f1 Nomenclature History
- Previous Names
-
- pou[c]
- pouc (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within atrioventricular canal morphogenesis. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in atrioventricular canal; atrium; cardiac ventricle; central nervous system; and telencephalon. Orthologous to human POU6F1 (POU class 6 homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Bhakta et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-specific domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z4C6 | InterPro | 574 | ||||||
| UniProtKB:P31367 | InterPro | 610 | ||||||
| UniProtKB:A0A2R8QIA3 | InterPro | 595 | ||||||
| UniProtKB:A0AB32TA53 | InterPro | 609 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou6f1-201
(1)
|
Ensembl | 4,090 nt | ||
| mRNA |
pou6f1-202
(1)
|
Ensembl | 525 nt | ||
| mRNA |
pou6f1-203
(1)
|
Ensembl | 1,871 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers