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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-481
Gene Name: Janus kinase 2a
Gene Symbol: jak2a
Sequence Ontology ID : SO:0000704

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Previous Name: Jak2a kinase

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity and non-membrane spanning protein tyrosine kinase activity; involved in several processes, including JAK-STAT cascade, animal organ development, and blood  ...
DISEASE ASSOCIATED WITH jak2a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acute myeloid leukemia Leukemia, acute myeloid, somatic 601626
Budd-Chiari syndrome {Budd-Chiari syndrome, somatic} 600880
essential thrombocythemia Thrombocythemia 3 614521
familial erythrocytosis 1 Erythrocytosis, somatic 133100
myelofibrosis Myelofibrosis, somatic 254450
polycythemia vera Polycythemia vera, somatic 263300
DISEASE ASSOCIATED WITH jak2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of receptor signaling pathway via JAK-STAT (more)
Cellular Component cytoskeleton (more)
Molecular Function ATP binding (more)
GO Terms (all 30)
TRANSCRIPTS
Type Name Length (bp) Analysis
ncRNA jak2a-002 (1) 579
jak2a-003 (1) 656
jak2a-004 (1) 607
jak2a-005 (1) 3703
mRNA jak2a-203 (1) 4315
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM jak2a No data available
MARKER RELATIONSHIPS
jak2aContained in: [Fosmid] ZFOS-1462C8 (1)
jak2aEncodes: [cDNA] MGC:193868 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131093 (1) 4387bp
Genomic GenBank:CU694470 (1) 41108bp
Select Tool
Polypeptide UniProtKB:F1QWX8 (1) 1095aa
Sequence Clusters UniGene:4151 (1)
Sequence Information (all 17)
ORTHOLOGY for jak2a (Chr: 21)
CITATIONS (51)