Gene

wnt2

ID
ZDB-GENE-980526-416
Name
wingless-type MMTV integration site family member 2
Symbol
wnt2 Nomenclature History
Previous Names
  • etID309852.18 (1)
  • ZfWnt2 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have cytokine activity and frizzled binding activity. Involved in hepatocyte proliferation and swim bladder development. Predicted to localize to extracellular space. Is expressed in several structures, including nervous system; optic cup; optic vesicle; otic vesicle; and swim bladder bud. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Poulain et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt2 Human Ortholog
No data available
Associated With wnt2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR009140 Wnt-2 protein
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt-2 protein Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:A0M8V9 282
UniProtKB:Q92048 350
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations