ZFIN is now using GRCz12tu for Genomic Data
Gene
pou3f1
- ID
- ZDB-GENE-980526-372
- Name
- POU class 3 homeobox 1
- Symbol
- pou3f1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within brain development; cell differentiation; and regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in several structures, including forebrain neural rod; hindbrain neural keel; nervous system; neural plate; and presumptive diencephalon. Orthologous to human POU3F1 (POU class 3 homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 36 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu433 (22 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Zhang et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR016362 | POU-domain transcription factor, class 3 |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-domain transcription factor, class 3 | POU-specific domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q90482 | InterPro | 368 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou3f1-201
(1)
|
Ensembl | 2,870 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers