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ZIRC
ZFIN ID: ZDB-GENE-980526-365
Gene Name: homeobox A13b
Gene Symbol: hoxa13b    Nomenclature History

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Previous Names: Hoxa-13, wu:fa66g07, zgc:110514

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in hand-foot-genital syndrome. Is expressed in several structures, including chondroblast; mesenchyme; pectoral fin bud; pectoral fin field; and tail bud. Orthologous to human HOXA13 (homeobox A13).
Genome Resources: Alliance (1),  Gene:30438 (1),  Ensembl(GRCz11):ENSDARG00000036254 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ch308 Indel Exon 1 Unknown CRISPR
hu3581 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hoxa13b 1
    CRISPR2-hoxa13b 1
    MO1-hoxa13b N/A 1
    DISEASE ASSOCIATED WITH hoxa13b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Guttmacher syndrome Alliance ?Guttmacher syndrome 176305
    hand-foot-genital syndrome Alliance Hand-foot-uterus syndrome 140000
    DISEASE ASSOCIATED WITH hoxa13b VIA EXPERIMENTAL MODELS No data available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxa13b-201 (1)    Ensembl 1546
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxa13b No data available
    MARKER RELATIONSHIPS
    hoxa13b Contained in: [BAC] DKEY-45E15 (1) (order this)
    hoxa13b Encodes: [EST] eu282 (1), fa66g07 (1)
    [cDNA] MGC:110514 (1) (order this), MGC:192624 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131194 (1) 858 bp
    Genomic GenBank:CR392024 (1) 183486 bp
    Select Tool
    Polypeptide UniProtKB:P79724 (1) 289 aa
    Sequence Clusters UniGene:15718 (1)
    Sequence Information (all 23)
    ORTHOLOGY for hoxa13b ( Chr: 16 )
    CITATIONS (57)