Gene

hoxa13b

ID
ZDB-GENE-980526-365
Name
homeobox A13b
Symbol
hoxa13b Nomenclature History
Previous Names
  • Hoxa-13
  • wu:fa66g07
  • zgc:110514
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in fin development and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including chondroblast; pectoral fin; pectoral fin bud; pectoral fin field; and tail bud. Human ortholog(s) of this gene implicated in Guttmacher syndrome and hand-foot-genital syndrome. Orthologous to human HOXA13 (homeobox A13).
Genome Resources
Note
None
Expression
All Expression Data
18 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa13b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Guttmacher syndrome Alliance ?Guttmacher syndrome 176305
hand-foot-genital syndrome Alliance Hand-foot-uterus syndrome 140000
Associated With hoxa13b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR022067 Homeobox protein Hox1A3 N-terminal
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Homeobox protein Hox1A3 N-terminal
UniProtKB:P79724 289
UniProtKB:B5DDS3 274
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations