Gene

pou3f2a

ID
ZDB-GENE-980526-139
Name
POU class 3 homeobox 2a
Symbol
pou3f2a Nomenclature History
Previous Names
  • brn1.2
  • id:ibd5088
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in brain; neural keel; neural plate; and spinal cord. Orthologous to human POU3F2 (POU class 3 homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Kasher et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pou3f2a Human Ortholog
No data available
Associated With pou3f2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR000327 POU-specific domain
Domain IPR001356 Homeobox domain
Domain IPR013847 POU domain
Family IPR016362 POU-domain transcription factor, class 3
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Homologous_superfamily IPR010982 Lambda repressor-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Lambda repressor-like, DNA-binding domain superfamily POU domain POU-domain transcription factor, class 3 POU-specific domain
UniProtKB:A2VD21 337
UniProtKB:Q90434 113
UniProtKB:Q6NW84 334
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Gates, et al. (1999. Genome Res. 9:334-347.) reported orthology to human POU3F1 and mouse Pou3f1. Subsequent analysis suggests this gene is the ortholog of human POU3F2 and mouse Pou3f2 based on amino acid identity and conserved location.
Citations