ZFIN is now using GRCz12tu for Genomic Data
Gene
pou3f2a
- ID
- ZDB-GENE-980526-139
- Name
- POU class 3 homeobox 2a
- Symbol
- pou3f2a Nomenclature History
- Previous Names
-
- brn1.2
- id:ibd5088
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within brain development and regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in brain; neural keel; neural plate; and spinal cord. Orthologous to human POU3F2 (POU class 3 homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kasher et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR000327 | POU-specific domain |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR013847 | POU domain |
| Family | IPR016362 | POU-domain transcription factor, class 3 |
| Family | IPR050255 | POU domain transcription factor |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR010982 | Lambda repressor-like, DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily | POU domain | POU domain transcription factor | POU-domain transcription factor, class 3 | POU-specific domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A2VD21 | InterPro | 337 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pou3f2a-201
(1)
|
Ensembl | 2,725 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers