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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-123
Gene Name: Janus kinase 2b
Gene Symbol: jak2b
Sequence Ontology ID : SO:0000704

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Previous Name: Jak2b kinase

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have ATP binding activity; histone binding activity; and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in erythrocyte differentiation. Predicted to  ...
PHENOTYPE No data available
DISEASE ASSOCIATED WITH jak2b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acute myeloid leukemia Leukemia, acute myeloid, somatic 601626
Budd-Chiari syndrome {Budd-Chiari syndrome, somatic} 600880
essential thrombocythemia Thrombocythemia 3 614521
familial erythrocytosis 1 Erythrocytosis, somatic 133100
myelofibrosis Myelofibrosis, somatic 254450
polycythemia vera Polycythemia vera, somatic 263300
DISEASE ASSOCIATED WITH jak2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process intracellular signal transduction (more)
Cellular Component cytoskeleton (more)
Molecular Function ATP binding (more)
GO Terms (all 25)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA jak2b-203 (1) 3389
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM jak2b No data available
MARKER RELATIONSHIPSNo data available
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131087 (1) 4536bp
Genomic GenBank:CABZ01049033 (1) 19564bp
Polypeptide UniProtKB:C0RW38 (1) 1126aa
Sequence Clusters UniGene:81254 (1)
Sequence Information (all 19)
ORTHOLOGY for jak2b (Chr: 5)
CITATIONS (29)