Gene
casp21
- ID
- ZDB-GENE-190425-1
- Name
- caspase 21, apoptosis-related cysteine peptidase
- Symbol
- casp21 Nomenclature History
- Previous Names
-
- casp7l (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cysteine-type endopeptidase activity and enzyme activator activity. Predicted to be involved in several processes, including erythrocyte differentiation; keratinocyte differentiation; and positive regulation of neuron apoptotic process. Predicted to be part of death-inducing signaling complex. Predicted to be active in cytoplasm. Is expressed in cranial blood vessel; intestinal bulb; muscle cell; nervous system; and pharyngeal arch.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Spead et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Family | IPR052039 | Caspase-related proteases and regulators |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Caspase-like domain superfamily | Caspase-related proteases and regulators | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7F386 | InterPro | 266 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
casp21-201
(1)
|
Ensembl | 801 nt |
Interactions and Pathways
No data available
Plasmids
No data available