Gene

lrrn3b

ID

ZDB-GENE-170217-3

Name

leucine rich repeat neuronal 3b

Symbol

lrrn3b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to be active in extracellular matrix and extracellular space. Used to study schizophrenia.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Thyme et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrrn3b Human Ortholog

No data available

Associated With lrrn3b Via Experimental Models

Human Disease	Fish	Conditions	Citations
schizophrenia	lrrn3b^a294/a294	standard conditions	Thyme et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000483	Cysteine-rich flanking region, C-terminal
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Additional Resources	Length	Cysteine-rich flanking region, C-terminal	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin domain subtype	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype
UniProtKB:H9GYJ3	InterPro	706
UniProtKB:A0A8M3AR64	InterPro	706

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	lrrn3-201 (1) Ensembl	Ensembl		2,121 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations