Gene

nfx1

ID

ZDB-GENE-160728-101

Name

nuclear transcription factor, X-box binding 1

Symbol

nfx1 Nomenclature History

Previous Names

si:dkey-10f23.2

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nfx1 Human Ortholog

No data available

Associated With nfx1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000967	Zinc finger, NF-X1-type
Domain	IPR001374	R3H domain
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR019787	Zinc finger, PHD-finger
Domain	IPR034076	Transcriptional repressor NF-X1, R3H domain
Family	IPR034078	Transcription factor NFX1 family
Homologous_superfamily	IPR036867	R3H domain superfamily

Domain Details Per Protein

Protein	Length	R3H domain	R3H domain superfamily	Transcriptional repressor NF-X1, R3H domain	Transcription factor NFX1 family	Zinc finger, NF-X1-type	Zinc finger, PHD-finger	Zinc finger, RING-type
UniProtKB:A0A1D5NSC5 InterPro	1083

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:dkey-10f23.2-201 (1) Ensembl	Ensembl	3,867 nt	Select Tool
ncRNA	si:dkey-10f23.2-002 (1) Ensembl	Ensembl	594 nt	Select Tool
ncRNA	si:dkey-10f23.2-003 (1) Ensembl	Ensembl	651 nt	Select Tool
ncRNA	si:dkey-10f23.2-004 (1) Ensembl	Ensembl	343 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations