ZFIN ID: ZDB-GENE-140513-1
Gene Name: dual specificity phosphatase 27
Gene Symbol: dusp27    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have protein tyrosine/serine/threonine phosphatase activity. Involved in skeletal myofibril assembly. Predicted to localize to the sarcomere. Is expressed in optic tectum and somite. Orthologous to human DUSP27 (dual specificity phosphatase 27, atypical).
Genome Resources: Alliance (1),  Gene:792623 (1)
GENE EXPRESSION
All Expression Data: Fig. 4 from Fero et al., 2014
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
y241Et Transgenic Insertion Unknown Splice Site DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dusp27 N/A 1
    DISEASE ASSOCIATED WITH dusp27 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dusp27 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process skeletal myofibril assembly (more)
    Cellular Component cytoplasm (more)
    Molecular Function phosphatase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000340 Dual specificity phosphatase, catalytic domain
    Domain IPR000387 Tyrosine specific protein phosphatases domain
    Family IPR020405 Atypical dual specificity phosphatase, subfamily A
    Family IPR020417 Atypical dual specificity phosphatase
    Domain IPR020422 Dual specificity protein phosphatase domain
    Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dusp27 No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_003197607 (1)
    Genomic GenBank:CABZ01080368 (1)
    Polypeptide UniProtKB:A9JR97 (1) 1102 aa
    Sequence Information (all 13)
    ORTHOLOGY for dusp27 ( Chr: 1 )
    CITATIONS (15)