Gene
elmo2
- ID
- ZDB-GENE-140106-84
- Name
- engulfment and cell motility 2
- Symbol
- elmo2 Nomenclature History
- Previous Names
-
- zmp:0000001124 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to be involved in cell migration; cell-cell adhesion; and cytoskeleton organization. Is expressed in brain; mid cerebral vein; and retinal ganglion cell layer. Orthologous to human ELMO2 (engulfment and cell motility 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Boger et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Vascular malformation, primary intraosseous | 606893 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR006816 | ELMO domain |
| Domain | IPR024574 | ELMO, armadillo-like helical domain |
| Family | IPR050868 | Engulfment and cell motility domain-containing protein |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | ELMO, armadillo-like helical domain | ELMO domain | Engulfment and cell motility domain-containing protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0JMQ5
|
704 | |||||||
|
UniProtKB:A0A8M1NXH9
|
711 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance