ZFIN is now using GRCz12tu for Genomic Data
Gene
cuzd1.1
- ID
- ZDB-GENE-131122-16
- Name
- CUB and zona pellucida-like domains 1, tandem duplicate 1
- Symbol
- cuzd1.1 Nomenclature History
- Previous Names
-
- fb66a12
- si:ch211-208g24.5
- wu:fb66a12
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including RNA-DNA hybrid ribonuclease activity; RNA-directed DNA polymerase activity; and zinc ion binding activity. Predicted to act upstream of or within DNA integration and proteolysis. Predicted to be active in cell surface and extracellular space. Orthologous to human CUZD1 (CUB and zona pellucida like domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR001969 | Aspartic peptidase, active site |
| Domain | IPR000477 | Reverse transcriptase domain |
| Domain | IPR001584 | Integrase, catalytic core |
| Domain | IPR001878 | Zinc finger, CCHC-type |
| Domain | IPR041577 | Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain |
| Domain | IPR041588 | Integrase zinc-binding domain |
| Domain | IPR048270 | Paraneoplastic antigen Ma-like, C-terminal domain |
| Family | IPR050951 | Retrovirus-related Pol polyprotein |
| Homologous_superfamily | IPR012337 | Ribonuclease H-like superfamily |
| Homologous_superfamily | IPR021109 | Aspartic peptidase domain superfamily |
| Homologous_superfamily | IPR036397 | Ribonuclease H superfamily |
| Homologous_superfamily | IPR036875 | Zinc finger, CCHC-type superfamily |
| Homologous_superfamily | IPR043128 | Reverse transcriptase/Diguanylate cyclase domain |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Aspartic peptidase, active site | Aspartic peptidase domain superfamily | DNA/RNA polymerase superfamily | Integrase, catalytic core | Integrase zinc-binding domain | Paraneoplastic antigen Ma-like, C-terminal domain | Retrovirus-related Pol polyprotein | Reverse transcriptase/Diguanylate cyclase domain | Reverse transcriptase domain | Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain | Ribonuclease H-like superfamily | Ribonuclease H superfamily | Zinc finger, CCHC-type | Zinc finger, CCHC-type superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P0J8 | InterPro | 1737 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cuzd1.1-201
(1)
|
Ensembl | 1,934 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers