Gene
si:zfos-411a11.2
- ID
- ZDB-GENE-131119-33
- Name
- si:zfos-411a11.2
- Symbol
- si:zfos-411a11.2 Nomenclature History
- Previous Names
-
- zmp:0000000718
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including drug dependence (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including CYP2C18 (cytochrome P450 family 2 subfamily C member 18); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017972 | Cytochrome P450, conserved site |
| Family | IPR001128 | Cytochrome P450 |
| Family | IPR002401 | Cytochrome P450, E-class, group I |
| Family | IPR008067 | Cytochrome P450, E-class, group I, CYP2A-like |
| Family | IPR050182 | Cytochrome P450 family 2 |
| Homologous_superfamily | IPR036396 | Cytochrome P450 superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450, E-class, group I, CYP2A-like | Cytochrome P450 family 2 | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YUY2 | InterPro | 491 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:zfos-411a11.2-201
(1)
|
Ensembl | 1,114 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance