Gene
nmur3
- ID
- ZDB-GENE-130530-567
- Name
- neuromedin U receptor 3
- Symbol
- nmur3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable neuropeptide receptor activity. Acts upstream of or within circadian behavior. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brainstem; forebrain; and hypothalamus.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Chiu et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chiu et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
ct829 | Allele with one deletion | Unknown | Unknown | TALEN | |
sa13171 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa21931 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa31837 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa41855 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Neuromedin U receptor |
---|---|---|---|---|---|
UniProtKB:A0A286YBK1 | InterPro | 392 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-220M17 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_009306091 (1) | |||
Genomic | GenBank:BX248318 (1) | 194209 nt | ||
Polypeptide | UniProtKB:A0A286YBK1 (1) | 392 aa |
- Comparative Orthology
- Alliance
No data available
- Ohlebusch, B., Borst, A., Frankenbach, T., Klopocki, E., Jakob, F., Liedtke, D., Graser, S. (2020) Investigation of alpl expression and Tnap-activity in zebrafish implies conserved functions during skeletal and neuronal development. Scientific Reports. 10:13321
- Chiu, C.N., Rihel, J., Lee, D.A., Singh, C., Mosser, E.A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B.J., Montz, C.J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A.F., Prober, D.A. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89:842-856
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