ZFIN is now using GRCz12tu for Genomic Data
Gene
jag2a
- ID
- ZDB-GENE-130530-549
- Name
- jagged canonical Notch ligand 2a
- Symbol
- jag2a Nomenclature History
- Previous Names
-
- zmp:0000000546 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable Notch binding activity. Acts upstream of or within epidermal cell differentiation. Predicted to be located in plasma membrane. Is expressed in ectoderm; ionocyte progenitor cell; pronephros; and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 27. Orthologous to human JAG2 (jagged canonical Notch ligand 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lu et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive limb-girdle muscular dystrophy type 27 | Alliance | Muscular dystrophy, limb-girdle, autosomal recessive 27 | 619566 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance