Gene

dlc1

ID
ZDB-GENE-130206-12
Name
DLC1 Rho GTPase activating protein
Symbol
dlc1 Nomenclature History
Previous Names
  • unm_sa1141
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity and lipid binding activity. Predicted to be involved in regulation of Rho protein signal transduction and signal transduction. Predicted to localize to cell junction and cytoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dlc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
colorectal cancer Alliance Colorectal cancer, somatic 114500
Associated With dlc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000198 Rho GTPase-activating protein domain
Domain IPR001660 Sterile alpha motif domain
Domain IPR002913 START domain
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR023393 START-like domain superfamily
Domain Details Per Protein
Protein Length Rho GTPase-activating protein domain Rho GTPase activation protein START domain START-like domain superfamily Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily
UniProtKB:E7FBY0
UniProtKB:A0A8M9PK49 1191
UniProtKB:A0A8M6Z677 1669
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations