Gene

tpp2

ID
ZDB-GENE-121214-290
Name
tripeptidyl peptidase 2
Symbol
tpp2 Nomenclature History
Previous Names
  • si:ch73-244f7.4
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have tripeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytosol. Orthologous to human TPP2 (tripeptidyl peptidase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Yang et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tpp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Immunodeficiency 78 with autoimmunity and developmental delay 619220
Associated With tpp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR022398 Peptidase S8, subtilisin, His-active site
Active_site IPR023828 Peptidase S8, subtilisin, Ser-active site
Domain IPR000209 Peptidase S8/S53 domain
Domain IPR022229 Peptidase S8A, tripeptidyl peptidase II
Domain IPR034051 Tripeptidyl-peptidase II domain
Family IPR015500 Peptidase S8, subtilisin-related
Homologous_superfamily IPR036852 Peptidase S8/S53 domain superfamily
Domain Details Per Protein
Protein Length Peptidase S8A, tripeptidyl peptidase II Peptidase S8/S53 domain Peptidase S8/S53 domain superfamily Peptidase S8, subtilisin, His-active site Peptidase S8, subtilisin-related Peptidase S8, subtilisin, Ser-active site Tripeptidyl-peptidase II domain
UniProtKB:R4GDQ0 1263
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations