tubgcp6

ID

ZDB-GENE-121205-1

Name

tubulin gamma complex component 6

Symbol

tubgcp6 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable gamma-tubulin binding activity. Predicted to be located in centrosome. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 1. Orthologous to human TUBGCP6 (tubulin gamma complex component 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Zhang et al., 2026
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tubgcp6 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
microcephaly and chorioretinopathy 1	Alliance	Microcephaly and chorioretinopathy, autosomal recessive, 1	251270

Associated With tubgcp6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040457	Gamma tubulin complex component, C-terminal
Domain	IPR041470	Gamma tubulin complex component protein, N-terminal
Domain	IPR045818	Gamma-tubulin complex component 6, N-terminal
Family	IPR047181	DCC-interacting protein 13-alpha/beta
Homologous_superfamily	IPR042241	Gamma tubulin complex component, C-terminal domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M1RLC1	InterPro	1844
UniProtKB:A0AC58IX34	InterPro	1954
UniProtKB:A0AC58IX38	InterPro	1927
UniProtKB:A0AC58IX44	InterPro	1981
UniProtKB:A0AC58IX48	InterPro	1954
UniProtKB:A0AC58IX56	InterPro	1214