Gene
muc5.2
- ID
- ZDB-GENE-121108-1
- Name
- mucin 5.2
- Symbol
- muc5.2 Nomenclature History
- Previous Names
-
- muc5b
- unm_sa927
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to be active in extracellular matrix and extracellular space. Is expressed in pharynx. Human ortholog(s) of this gene implicated in bronchiolitis; dry eye syndrome; idiopathic pulmonary fibrosis; interstitial lung disease 2; and urinary bladder cancer. Orthologous to human MUC5AC (mucin 5AC, oligomeric mucus/gel-forming) and MUC5B (mucin 5B, oligomeric mucus/gel-forming).
- Genome Resources
- Note
-
This gene is orthologous to BOTH human MUC5AC and MUC5B (evidence: amino acid alignment, phylogenetic tree and synteny). The nomenclature has been updated to avoid implying an orthologous relationship to only one of these genes.
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018245 | Gonadotropin, beta subunit, conserved site |
| Domain | IPR001007 | VWFC domain |
| Domain | IPR001846 | von Willebrand factor, type D domain |
| Domain | IPR002919 | Trypsin Inhibitor-like, cysteine rich domain |
| Domain | IPR006207 | Cystine knot, C-terminal |
| Domain | IPR014853 | VWF/SSPO/Zonadhesin-like, cysteine-rich domain |
| Family | IPR050780 | Mucin/von Willebrand/Thrombospondin superfamily |
| Homologous_superfamily | IPR036084 | Serine protease inhibitor-like superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cystine knot, C-terminal | Gonadotropin, beta subunit, conserved site | Mucin/von Willebrand/Thrombospondin superfamily | Serine protease inhibitor-like superfamily | Trypsin Inhibitor-like, cysteine rich domain | von Willebrand factor, type D domain | VWFC domain | VWF/SSPO/Zonadhesin-like, cysteine-rich domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0AB32TF33 | InterPro | 6126 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
muc5.2-201
(1)
|
Ensembl | 18,751 nt | ||
| mRNA |
muc5.2-202
(1)
|
Ensembl | 648 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance