Gene

ptgir

ID
ZDB-GENE-120511-1
Name
prostaglandin I2 receptor
Symbol
ptgir Nomenclature History
Previous Names
  • PRS1 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Enables prostacyclin receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of smooth muscle cell proliferation; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human PTGIR (prostaglandin I2 receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Tsuge et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Nijoukubo et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptgir Human Ortholog
No data available
Associated With ptgir Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000370 Prostacyclin (prostanoid IP) receptor
Family IPR008365 Prostanoid receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Prostacyclin (prostanoid IP) receptor Prostanoid receptor
UniProtKB:E7FE45 364
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations